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What is hCG?
(hCG) Human chorionic gonadotropin or human chorionic gonadotrophin - is a glycoprotein hormone produced in highest levels during pregnancy. Like other gonadotropins, hCG can be extracted from urine.
hCG and Weight loss
A controversial usage of hCG is as an adjunct to the British endocrinologist A.T.W. Simeons' ultra-low-calorie weight-loss diet (less than 500 calories). Simeons, while studying pregnant women in India on a calorie-deficient diet, and “fat boys” with pituitary problems treated with low-dose hCG, claimed that both lost fat rather than lean (muscle) tissue. He reasoned that hCG must be programming the hypothalamus to do this in the former cases in order to protect the developing fetus by promoting mobilization and consumption of abnormal, excessive adipose deposits. Simeons, practicing at Salvator Mundi International Hospital in Rome, Italy, recommended low-dose daily hCG injections (125 IU) in combination with a customized ultra-low-calorie (500 cal/day, high-protein, low-carbohydrate/fat) diet loss of adipose tissue without loss of lean tissue.
Other Clinical Uses for hCG
hCG is clinically used both to induce ovulation and treat certain ovarian disorders in women. In men hCG is utilized to stimulate the testes in hypogonadal men (men who are not producing testosterone). It has also shown promise in the treatment of undescended testicles in young males.
In an indirect way via the anterior pituitary, hCG regulates menstruation and facilitates conception, but it never virilizes a woman or feminizes a man. It neither makes men grow breasts nor does it interfere with their virility, though where this was deficient it may improve it. It never makes women grow a beard or develop a gruff voice.
Effects of hCG on Men
Human Chorionic Gonadotropin is a substance that, in the human body, mimics Leutenizing Hormone (LH). LH is secreted by your body, and its secretion then signals the body to begin releasing testosterone.
hCG is typically employed by steroid-using athletes to bring back some naturally produced testosterone into their bodies. However, hCG is clinically used both to induce ovulation and treat certain ovarian disorders in women.
In men is utilized to stimulate the testes in hypogonadal men (men who are not producing testosterone). It has also shown promise in the treatment of undescended testicles in young males.
The action of hCG in males is very similar to that of LH, because they are chemically similar and since LH binds to receptors on human Leydig cells, we see a similar mechanism of action with hCG. Once it binds and begins to stimulate the receptors on the Leydig cells, it begins to trigger the synthesis and secretion of testosterone. However, hCG will only send an “artificial” signal to the testes through Leydig cell stimulation. Thus, it is possible that hCG use can cause Leydig cell desensitization. I don’t know of anyone who has actually experienced this, nor who has even claimed that it’s happened to either them or a friend, or whatever- anecdotal evidence here is scarce.
There are two schools of thought regarding hCG use, and neither are very new. In fact, both have been around since the earliest books on underground steroid use, and were spoken about more than a decade ago by Dan Duchaine (Underground Steroid Handbook) and also by W. Nathaniel Phillips (Anabolic Reference Guide volumes 1-6).
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